Certified Reference Materials (CRM) serve as internal controls to continuously monitor the quality of existing analytical methods and validate/verify new ones. Each CRM is accompanied by a certificate ensuring metrological traceability to the specific target organisms, expected level, and range with a 95% confidence interval.

Eurofins offers CRMs containing multiple target organisms simultaneously. They are available in two formats; powdered or freeze-dried. The powdered format is presented as a set of 5 sachets while the freeze-dried material is presented as a set of 3 vials. Regular testing with these materials, yielding satisfactory results, builds confidence in the laboratory’s ability to consistently produce reliable results.

The reference materials are user-friendly, and applicable for both quantitative and qualitative analyses. They serve as a positive control for the method in question, while also serving as negative controls and/or background flora. They can be utilized as a stand-alone test, or they can be added to a chosen matrix. They are ideal for training of new staff.

 

Applications

• Daily or regular qualitative or quantitative control
• control of media
• training of staff
• method validation/verification/comparison
• establishing measurement uncertainty

CRM can be used with most techniques within microbiology, such as direct counting, surface plating, pour plate methods, rapid methods, PCR, membrane filtration etc.

CRM Certificates

Understanding key points is essential for effective usage of the CRM certificates.

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CRM Detection Tests

Learn how to use CRM with your detection tests.

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Valid CRM certificates

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CRMs available:

CRM	Purpose	Format	Set	Target organisms	Examples of analysis
MV0029	Universal control, for water and food	Freeze-dried	3 vials	Bacillus cereus Clostridium perfringens Enterococcus faecalis Escherichia coli Klebsiella aerogenes Pseudomonas aeruginosa	Plate count, Enterobacteriaceae, coliform bacteria, thermotolerant coliform bacteria, E. coli (quant/qual), enterococcus (water/food), C. perfringens, anaerobic sulfite reducing bacteria, P. aeruginosa, presumptive Bacillus cereus
FM0046	Pathogen control	Powder	5 sachets	Listeria monocytogenes Salmonella Hofit	Quantitative or qualitative
FM0030	Hygiene control - coliforms, mould and yeast	Powder	5 sachets	Klebsiella aerogenes Escherichia coli Aspergillus niger Candida utilis	Plate count, Enterobacteriaceae, coliform bacteria, thermotolerant coliform bacteria, E. coli, mould, yeast
FM0031	Gram positive control	Powder	5 sachets	Bacillus cereus Lacticaseibacillus rhamnosus Staphycococcus aureus	Plate count, presumptive Bacillus cereus, lactic acid bacteria, coagulase positive Staphylococcus
MV0037	Legionella control	Freeze-dried	3 vials	Fluoribacter bozemanae Legionella pneumophila SG1	Legionella total, Legionella spp., Legionella pneumophila SG1